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Biaryl PDE4 inhibitors for treating inflammatory, cardiovascular and CNS disorders
专利权人:
Vincent Sandanayaka;Georgeta Hategan;Alexander Kiselyov;Timothy Hagen;Mark E. Gurney;Jasbir Singh;Adalie Motta;Alex Burgin;Gary Schiltz
发明人:
Jasbir Singh,Mark E. Gurney,Alex Burgin,Vincent Sandanayaka,Alexander Kiselyov,Adalie Motta,Gary Schiltz,Georgeta Hategan,Timothy Hagen
申请号:
US13430164
公开号:
US08791267B2
申请日:
2012.03.26
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates to a genus of biaryl compounds containing at least one further ring. The compounds are PDE4 inhibitors useful for the treatment and prevention of stroke, myocardial infarct and cardiovascular inflammatory diseases and disorders. The compounds have general formula I:A particular embodiment is
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