The present disclosure describes pharmaceutical compositions and methods for cleansing the nose, clearing the nose, imparting a cooling sensation in the nose, moisturizing nasal passages, soothing a dry nose, and ameliorating dehydration of the anterior nasal mucosa in humans in need of relief thereof. The compositions herein comprise humectants such as Aloe barbadensis leaf gel, hyaluronic acid, and/or a hyaluronate salt in a buffered and thickened pharmaceutically acceptable carrier. In various aspects, methods for relief comprise nasally administering compositions comprising Aloe barbadensis leaf gel and sodium hyaluronate in a pharmaceutically acceptable carrier to a human in need of relief thereof.
