A manual resuscitator regulating system for regulating the rate and volume of ventilation during manual resuscitation. The manual resuscitator regulating system may include an intake assembly configured to permit a selected volume of gas to flow into a chamber over a predetermined amount of time and/or an outtake assembly configured to permit a selected volume of gas flow out of the chamber over a predetermined amount of time. The intake assembly and/or the outtake assembly may include one or more adjustment mechanisms configured to allow a user to selectively adjust volume. The intake assembly and the outtake assembly may be configured to coordinate with one another to deliver a selected tidal volume and/or volume of gas. The manual resuscitator regulating system may include a placement indicator configured to indicate or guide a user where to squeeze or compress the chamber.