The present invention relates to a compound represented by the following formula (I) is the resorcinol derivative of HSP90 inhibitor or a pharmaceutically acceptable salt. The compounds can inhibit the activity of HSP90. The compound of the present invention could used to treat some diseases, like proliferative diseases of cancer and degeneration diseases of nervous system. The present invention also provided the prepared from about these compounds, pharmaceutical composition contained these compound, therapies of diseases.本發明關於一種作為HSP90抑制劑的間苯二酚類衍生物的式(I)化合物或其藥學上可接受的鹽類。本發明的化合物具有抑制熱休克蛋白HSP90的活性。本發明的化合物因此用於治療例如癌症的增殖疾病和神經變性疾病。本發明也提供了這些化合物和包含它們的藥物組合物的製備方法，治療疾病的方法和包含這些化合物的藥物組合物。
