Michael Des Jardin;Clark Allphin;Gene Jamieson;Sigridur Olafsdottir
发明人:
Gene Jamieson,Michael Des Jardin,Clark Allphin,Sigridur Olafsdottir
申请号:
US11897028
公开号:
US08609651B2
申请日:
2007.08.27
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention includes benzodiazepine compositions formulated for intranasal administration, comprising a binary solvent system comprising a first solvent in which the benzodiazepine is soluble, the first solvent capable of penetrating nasal mucosal tissue, and a second solvent in which the benzodiazepine in less soluble. The compositions of the present invention may be used to treat a variety of disorders including, but not limited to, panic attacks, muscle spasms, anxiety, and seizures. In one aspect, the present invention relates to a fast-acting, clonazepam composition for transnasal administration that can be used for the treatment of seizure clusters.