Stephen Benkovic,Ye Fang,Songon An,Florence Verrier
申请号：
US13185018
公开号：
US20120190620A1
申请日:
2011.07.18
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention discloses methods to identify targets, pathways and molecules regulating purinosomes and their uses for treating pathophysiological disorders associated with purinosomes. Disclosed are methods related to both label-free cellular assays and fluorescence imaging to confirm the regulatory roles of various targets and molecules in purinosome dynamics. Disclosed are methods to classify molecules and the uses of these molecules for different indications. Specifically, the purinosome-disrupting molecules can be used for improved prevention and treatment of cancer development.
