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TRAITEMENT DE L'HYPOGLYCÉMIE POST-BARIATRIQUE AVEC L'EXENDINE (9-39)
专利权人:
The Board of Trustees of the Leland Stanford Junior University
发明人:
申请号:
EP16800621.1
公开号:
EP3297654A4
申请日:
2016.05.23
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
Treatment of hyperinsulinemic hypoglycemia comprises administration of an effective amount of glucagon-like peptide-1 receptor antagonist (GLP1RA) exendin(9-39). Patients suffering from hyperinsulinemic hypoglycemia after bariatric surgery or gastrointestinal surgery experience particular benefit, as there is no current method effective for their treatment. Prevention or reduction of acute adverse effects of postprandial hypoglycemia, such as palpitations, tremor, weakness, sweating, confusion, fatigue, blurred vision, seizures, or loss of consciousness, and prevention of chronic adverse effects of hyperinsulinemic hypoglycemia, such as cognitive impairment, can be achieved by treatment with GLP1RA exendin(9-39).
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