PROBLEM TO BE SOLVED: To provide a therapeutic agent for chronic inflammatory disease, effective also to type 2 diabetes.SOLUTION: The therapeutic agent for chronic inflammatory disease contains a compound represented by formula (I) or its salt (in the formula, R1 represents a 1-6C alkyl group substituted with at least one group selected from substituted or nonsubstituted aromatic group and carboxyl group R2represents a hydrogen atom R3 represents a hydrogen atom, a substituted or nonsubstituted five-membered cyclic group or six-membered cyclic group, or a 1-6C alkyl group substituted with a substituted or nonsubstituted aromatic group and R4 and R5 are the same or different and each represents a hydrogen atom, a 1-6C alkyl group or a substituted or nonsubstituted aromatic group).COPYRIGHT: (C)2012,JPO&INPIT【課題】2型糖尿病にも有効な慢性炎症性疾患治療剤の提供。【解決手段】次式(I):(式中、R1は置換もしくは非置換の芳香族基及びカルボキシル基から選ばれる少なくとも1つの基で置換されたC1-6-アルキル基を表し;R2は水素原子を表し;R3は水素原子、置換もしくは非置換の5員環基又は6員環基、又は置換もしくは非置換の芳香族基で置換されたC1-6-アルキル基を表し;R4及びR5は同一又は異なり、水素原子、C1-6-アルキル基又は置換もしくは非置換の芳香族基を表す。)で示される化合物又はその塩を含有する慢性炎症性疾患治療剤。【選択図】なし
