Korea Research Institute of Chemical Technology;Handok Inc.
发明人:
Jung, Hee Jung,Ha, Jae Du,Cho, Sung Yun,Kim, Hyoung Rae,Lee, Kwang Ho,Lee, Chong Ock,Choi, Sang Un,Park, Chi Hoon
申请号：
AU2013402175
公开号：
AU2013402175A1
申请日:
2013.09.30
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
The present invention relates to a novel triazolopyrazine derivative or a pharmaceutically acceptable salt thereof； to a pharmaceutical composition containing the same as an active ingredient for inhibiting c-Met tyrosine kinase activity； and to a pharmaceutical composition for preventing or alleviating a hyper-proliferative disorder. The present invention efficiently inhibits c-Met tyrosine kinase activity, and thus can be useful as a therapeutic agent against various hyper-proliferative disorders associated with excessive cellular proliferation and growth due to abnormal kinase activity, for example, cancer, psoriasis, rheumatoid arthritis, or diabetic retinopathy.
