Compounds derived from 1h pyrazolo [3,4-b] pyridine as inhibitors of one or more proteins in the Wnt Pathway, which includes Pharmaceutical composition useful for the treatment of cancer, Diabetic Retinopathy, pulmonary fibrosis, rheumatoid arthritis, Alzheimer's disease, among others.

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专利权人:

LLC;SAMUMED

发明人:

HOOD JOHN,WALLACE DAVID MARK,KC SUNIL KUMAR

申请号：

CL2014002983

公开号：

CL2014002983A1

申请日:

2014.11.04

申请国别(地区):

CL

年份:

2015

代理人:

摘要：

Provided herein are compounds according to Formulas (I) or (II) and pharmaceutically acceptable salts thereof , and compositions comprising the same, for use in various methods, including treating cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease, lung disease, osteoarthritis, idiopathic pulmonary fibrosis and neurological conditions/disorders/diseases.“COMPUESTOS DERIVADOS DE 1H-PIRAZOLO[3,4-B]PIRIDINA, COMO INHIBIDORES DE UNA O MÁS PROTEÍNAS EN LA RUTA DEL WNT； COMPOSICIÓN FARMACÉUTICA QUE LOS COMPRENDE； Y SU USO EN EL TRATAMIENTO DEL CÁNCER, RETINOPATÍA DIABÉTICA, FIBROSIS PULMONAR, ARTRITIS, REUMATOIDE, ALZHEIMER, ENTRE OTRAS”. PCT

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/