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METHOD OF TREATING DEMYELINATING DISEASE
专利权人:
THE HOSPITAL FOR SICK CHILDREN
发明人:
MASTRONARDI, FABRIZIO,MOSCARELLO, MARIO A.,WOOD, DENISE
申请号:
CA2758829
公开号:
CA2758829C
申请日:
2009.04.17
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
A method of inhibiting Peptidyl Argininedeiminase (PAD) in a mammal isprovided wherein said method comprisesthe step of administering 2-haloacetamidine to a mammal. The method is usefulto treat a demyelinating disease in mammalssuch as multiple sclerosis, as well as other diseases in which hyper-citrullination is a factor. Pharmaceutical compositions useful totreat said disease are also provided, as well as a method of screening for PADinhibitors.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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