AKINOLA SOYODE-JOHNSON,BRAD M. SAVALL,BRETT D. ALLISON,BRICE M. STENNE,CHRISTA C. CHROVIAN,CHRISTINE F. GELIN,CURT A. DVORAK,DEVIN M. SWANSON,HEATHER R. COATE,JASON C. RECH,JESSICA L. WALL,JIMMY T. LI
申请号：
BR112015023142
公开号：
BR112015023142A2
申请日:
2014.03.14
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
abstract the present invention is directed to compounds of formulas (i, ia, iia and iib): the invention also relates to pharmaceutical compositions comprising compounds of formulas (i, ia, iia and iib). methods of making and using the compounds of formulas (ia, ia, ia and ib) are also within the scope of the invention. -------------------------------------------------- -------------------------------------------------- abstract of the patent summary: "p2x7 modulators". The present invention relates to the compounds of formulas (I, Ia, IIa and IIb): The invention also relates to pharmaceutical compositions comprising the compounds of the formulas (I, Ia, IIa and IIi). Methods for making and using the compounds of the formulas (I, Ia, Iia and Iib) are also within the scope of the invention.abstract the present invention is directed to compounds of formulas (i, ia, iia and iib): the invention also relates to pharmaceutical compositions comprising compounds of formulas (i, ia, iia and iib). methods of making and using the compounds of formulas (i, ia, iia and iib) are also within the scope of the invention. ----------------------------------------------------------------------------------------------------tradução do resumo resumo patente de invenção: "moduladores de p2x7". a presente invenção refere-se aos compostos de fórmulas (i, ia, iia e iib): a invenção refere-se também às composições farmacêuticas que compreendem os compostos de fórmulas (i, ia, iia e iib). os métodos para fazer e usar os compostos das fórmulas (i, ia, iia e iib) também estão dentro do escopo da invenção.
