Sung Jae Lee;Kab Sig Kim;Sang Heon Lee;Young Hoon Kim
发明人:
Sung Jae Lee,Young Hoon Kim,Sang Heon Lee,Kab Sig Kim
申请号:
US13497208
公开号:
US09393201B2
申请日:
2010.09.20
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to a nanoparticle of oxaliplatin, which is a water-soluble active substance, a pharmaceutical composition containing the same, and a method for preparing an orally administrable oxaliplatin nanoparticle by 5 emulsifying a lipid mixture solution wherein a solid lipid and a surfactant are mixed in an aqueous mixture solution wherein oxaliplatin and a specific cosolvent are mixed and then removing the solid lipid and the cosolvent using a supercritical fluid gas.