COMPLEXES ISSUS DU CYTOMEGALOVIRUS ET LEURS UTILISATIONS

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专利权人:

GLAXOSMITHKLINE BIOLOGICALS SA

发明人:

CARFI ANDREA,CARFI ANDREA,CHANDRAMOULI SUMANA,CHANDRAMOULI SUMANA,CIFERRI CLAUDIO,CIFERRI CLAUDIO,GERREIN RACHEL,GERREIN RACHEL,SETTEMBRE ETHAN,SETTEMBRE ETHAN,WEN YINGXIA,WEN YINGXIA

申请号：

BE201505327

公开号：

BE1023213A1

申请日:

2015.05.26

申请国别(地区):

BE

年份:

2016

代理人:

摘要：

This disclosure provides modified cytomegalovirus (CMV) gL proteins and complexes comprising gL proteins, in particular pentameric complexes comprising gH, gL, pUL128, pUL130, pUL131. The disclosure also provides methods of purifying pentameric complexes and reducing contaminating dimeric complexes consisting of gH and gL. Also provided are uses of pentameric complexes in immunogenic compositions and vaccines.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/