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Complexes of cytomegalovirus proteins
专利权人:
Novartis AG
发明人:
Carfi, Andrea,Wen, Yingxia
申请号:
AU2013286093
公开号:
AU2013286093A1
申请日:
2013.06.29
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
This disclosure provides an isolated human cytomegalovirus (HCMV) membrane protein complex, wherein said complex comprises gH, gL and at least one more HCMV glycoprotein. In some embodiments the complex consists of gH,gL and gO. In other embodiments the complex consists of gH, gL, p UL128, p UL130 and p UL131A. The disclosure also provides processes for expressing and purifying said complexes, and subsequent uses of said complexes in immunogenic compositions and vaccines.
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