A synergistic insecticidal composition comprises component (A), at least one neonicotinoid insecticide, and component (B), at least one avermectin insecticide. There is also provided a method to prevent, control and/or treat insect infestations in plants, plant parts and/or surrounding by applying a combination of component (A), at least one neonicotinoid insecticide, and component (B), at least one avermectin insecticide.協同殺昆蟲組合物包含組分(A)至少一種新尼古丁殺蟲劑和組分(B)至少一種伊維菌素殺蟲劑。還提供了用於藉由施用組分(A)至少一種新尼古丁殺蟲劑和組分(B)至少一種伊維菌素殺蟲劑之組合來預防、控制和/或處理植物、植物部分和/或周圍環境中的昆蟲侵染之方法。