The present invention is related to a combination comprising a first constituent and a second constituent, wherein the first constituent is a compound having the ability to rearrange a lysosomal protein, wherein the lysosomal protein has a reduced activity, and wherein the second constituent is Ambroxol and/or a derivative of Ambroxol.L'invention concerne le fait que les informations stockées sur le support qui est soumis ici à la demande de brevet internationale est identique au listage de séquence écrit de la demande de brevet internationale.