BOARD OF GOVERNORS FOR HIGHER EDUCATION; STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS
发明人:
ZAWIA, Nasser
申请号：
USUS2013/076953
公开号：
WO2014/100601A2
申请日:
2013.12.20
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A method is disclosed of reducing the level of tau protein in a subject's brain for the treatment of tau tangles. The method includes administrating an effective dose of drug that reduced Sp1 levels to the subject to lower tau mRNA and protein levels, CDK5 mRNA and protein levels, as well phosphorylated tau in the brain.
