DONGGUK UNIVERSITY INDUSTRY-ACADEMY COOPERATION FOUNDATION
发明人:
Gun Il Im,Mi Lan Kang
申请号:
US15505980
公开号:
US20170290791A1
申请日:
2015.08.11
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to kartogenin-conjugated chitosan particles with an improved sustained release property and biocompatibility. Effects of increases in biocompatibility, chondrogenic differentiation efficiency and retention time in the joints were confirmed by using kartogenin-chitosan microparticles or kartogenin-chitosan nanoparticles of the present invention, and thus targeted treatment, in the prevention or treatment of bone diseases, is enabled through a more fundamental approach.