The present invention relates to a composition comprising a) Streptomyces microflavus strain NRRL B-50550 and/or a mutant thereof having all the identifying characteristics of the respective strain, and/or at least one metabolite produced by the respective strain that exhibits activity against insects, mites, nematodes and/or phytopathogens and/or a mutant thereof having all the identifying characteristics of the respective strain, and/or at least one metabolite produced by the respective strain that exhibits activity against insects, mites, nematodes and/or phytopathogens and b) at least one further biological control agent selected from specific microorganisms and/or a mutant of it having all identifying characteristics of the respective strain, and/or at least one metabolite produced by the respective strain that exhibits activity against insects, mites, nematodes and/or phytopathogens in a synergistically effective amount. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.La présente invention concerne une composition comprenant a) de la gougérotine isolée, b) au moins un agent de lutte biologique sélectionné parmi des micro-organismes spécifiques et/ou un mutant de ceux-ci ayant toutes les caractéristiques d'identification de la souche respective, et/ou au moins un métabolite produit par la souche respective qui présente une activité contre les insectes, les mites, les nématodes, et/ou les phytopathogènes dans des quantités efficaces en synergie. De plus, la présente invention concerne l'utilisation de ces compositions ainsi qu'une méthode de réduction de la détérioration générale de plantes et de parties de plantes.
