PREPARATION AND EVALUATION OF NOVEL TARGETED DRUG DELIVERY OF METRONIDAZOLE TO THE COLON

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专利权人:

发明人:

SUKHBIR KAUR,RAJ KUMAR NARANG,TILAK RAJ BHARDWAJ

申请号：

IN2016/DEL/2015

公开号：

IN2015DE02016A

申请日:

2015.07.03

申请国别(地区):

IN

年份:

2017

代理人:

摘要：

This invention relates to the preparation and evaluation of novel targeted drug delivery of metronidazole to the colon. The present method includes preformulation studies of drug and carrier system which includes organoleptic properties, identification, saturation solubility, partition co-efficient and FTIR studies of metronidazole. Preparation and characterization of metronidazole- β-cyclodextrin inclusion complex. Formulation and optimization of eudragit S100 coated metronidazole granules and formulation and evaluation mucopenetrating nanoparticles of Eudragit S100 coated metronidazole chitosan HPMCP nanoparticles.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/