GILLBERG, PER-GORAN,GUSTAFSSON, NILS OVE,LOVGREN, KURT
申请号：
CA3071285
公开号：
CA3071285A1
申请日:
2018.08.09
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The invention relates to small granules comprising cholestyramine. The granules have a high cholestyramine content and are stable enough to be coated with one or more coating layers. The invention also relates to a multiparticulate drug delivery system comprising such granules.The invention further relates to an oral formulation for targeted delivery of cholestyramine to the colon, comprising a plurality of cholestyramine granules that are coated with a colon release coating. The invention also relates to the use of this formulation in the treatment of bile acid malabsorption and bile acid diarrhoea.
