KIM, BOK DEUK,김복득,KIM, JIN HEE,김진희,LEE, HYE JIN,이혜진,WHANG, GUI SEO,황귀서,PARK, JEONG HILL,박정일
申请号：
KR1020110123257
公开号：
KR1020130057517A
申请日:
2011.11.24
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: Healthy functional food containing brazilin is provided to suppress wrinkles and ultra violet-induced skin damages by controlling factors related to the production and decomposition of collagen.CONSTITUTION: Healthy functional food contains brazilin or pharmaceutically-acceptable salt thereof as an active ingredient. The healthy functional food is powder remedies, pills, capsules, and liquid formulation. A healthy food composition contains 0.01-15 weight% of brazilin or pharmaceutically-acceptable salt thereof to the total food weight. A healthy beverage composition contains 0.02-10g or desirably 0.3-1g of brazilin or pharmaceutically-acceptable salt thereof on the basis of 100 ml.COPYRIGHT KIPO 2013본 발명은 Brazilin은 UV의해 증가된 LDH의 유리, 니트라이트, MMP-1, c-fos, c-jun, iNOS 의 유전자 발현을 감소, UV에 의해 생성이 감소한 TIMP-1, 프로콜라겐, Bcl-2 유전자 발현을 증가시켜 콜라겐의 생성 및 분해에 관련된 인자들을 조절하여 주름살 억제 및 UV 유발 피부손상 억제를 확인함으로써 피부 주름의 예방 및 개선에 유용한 조성물을 제공할 수 있다.
