COMPOSITION FOR CURING AND PREVENTING DEGENERATIVE BRAIN DISEASES, CONTAINING A THIOADENOSINE DERIVATIVE AND PHARMACEUTICAL ACCEPTABLE SALTS THEREOF AS AN ACTIVE INGREDIENT
PURPOSE: A pharmaceutical composition or health functional food is provided to be useful for curing and preventing degenerative brain diseases by confirming a remarkable inhibitory activity of the compound to the brain ischemic damage and the migration of inflammatory cells in rats.CONSTITUTION: A pharmaceutical composition for curing and preventing degenerative brain diseases comprises a thioadenosine derivative represented by Chemical formula I, and pharmaceutically acceptable salts thereof as an active ingredient. The degenerative brain diseases are stroke, dementia, Alzheimer disease, Parkinson disease or Huntington disease. Health functional food for preventing and alleviating degenerative brain diseases comprises a thioadenosine derivative represented by Chemical formula I, and pharmaceutically acceptable salts thereof as an active ingredient. The food formulation is various food goods of candy, beverage, gum, tea, vitamin supplements, or health supplementary food. A food additive comprises a thioadenosine derivative represented by Chemical formula (1), and pharmaceutically acceptable salts thereof as an active ingredient.COPYRIGHT KIPO 2013본 발명은 티오아데노신 유도체 및 이의 약학적으로 허용가능한 염을 유효성분으로 함유하는 퇴행성 뇌질환 치료용 약학 조성물 또는 건강 기능 식품에 관한 것으로서, 상세하게는 본 발명의 티오아데노신 유도체는 래트에서의 뇌허혈성 손상 및 염증성 세포의 이주에 대하여 저해능이 탁월하므로 퇴행성 뇌질환 치료에 유용한 약학 조성물 또는 건강 기능 식품을 제공한다.
