Pingda Ren;Katrina Chan;Troy Edward Wilson;Yi Liu;Liansheng Li;Christian Rommel
发明人:
Pingda Ren,Yi Liu,Troy Edward Wilson,Katrina Chan,Christian Rommel,Liansheng Li
申请号:
US12811695
公开号:
US08703777B2
申请日:
2009.01.05
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Provided herein are substituted bicyclic compounds, e.g., compounds of Formula IV, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are useful for inhibiting phosphatidyl inositol-3 kinase (PI3 kinase), e.g., for the treatment of various diseases and conditions associated with PI3 kinase activity, including but not limited to, cancer, inflammatory disease, immune disease, and respiratory disease.