KIM, DAE JIN,KIM, MIN YOUNG,KIM, JIN SUN,HONG, SUNG HEE,JUNG, SUNG YOUB,KWON, SE CHANG
申请号：
EP11763095
公开号：
EP2552422A4
申请日:
2011.04.04
申请国别(地区):
EP
年份:
2014
代理人:
摘要：
The present invention relates to a long-acting interferon beta formulation having improved in vivo duration and stability, comprising an interferon beta conjugate that is prepared by covalently linking interferon beta with an immunoglobulin Fc region via a non-peptidyl polymer, and a preparation method thereof. The long-acting interferon beta formulation of the present invention maintains in vivo activity of interferon beta at a relatively high level and remarkably increases the serum half-life thereof, thereby being used for various diseases, for which interferon is efficacious.
