A method for treating a disease or disorder associated with retinal pigment epithelium (RPE) disturbance, comprising administering to a human in need thereof an effective amount of a black soybean (Glycine max (L.) Merr) product is provided, wherein the black soybean product is the seed coats of black soybean or an alcoholic extract of black soybean or seed coats thereof.本發明提供一種用於治療與視網膜色素上皮細胞(RPE)障礙相關之疾病或病症之方法,其包含對需要該治療之人類投以有效量之黑豆(Glycine max(L.)Merr)產物,其中該黑豆產物係黑豆之種皮,或是黑豆或其種皮之醇類萃取物。