Michel Nussenzweig,Ariel Halper-Stromberg,Ching-Lan Lu
申请号：
US16885797
公开号：
US20200299365A1
申请日:
2020.05.28
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to methods and agents for preventing the establishment of HIV-1 latent reservoirs or for reducing the size of the reservoirs. Specifically, the disclosure provides methods and agents for preventing the establishment of HIV-1 latent reservoirs or for reducing the size of the reservoirs, the methods comprising administering to the subject a therapeutically effective amount of an isolated anti-HIV antibody, and administering to the subject two or more viral transcription inducers in effective amounts to induce transcription of an HIV provirus in the cells. Further provided are antibodies and viral transcription inducers used in the methods.
