MICHAEL P. VITEK P,SUZANNE E. MCKENNA E,CHRISTOPHER R. SELF R,‧麥克納,克里斯托弗‧,‧塞爾夫,邁克爾‧,‧維特克,蘇珊‧
申请号:
HK08105621.8
公开号:
HK1110805B
申请日:
2008.05.21
申请国别(地区):
HK
年份:
2015
代理人:
摘要:
Novel ApoE peptides derivatives and ApoE-protein transduction domain conjugates are disclosed which are useful for treating disorders including CNS inflammation, traumatic brain injury, inflammatory bowel disease (also know as Crohn's Disease or ulcerative colitis), cerebral ischemia, atherosclerosis, sepsis, multiple sclerosis and arthritic diseases, Alzheimer's Disease and other brain disorders. The invention encompasses methods for protecting subjects having undergone irradiation or radiotherapy by administration of ApoE or at least one ApoE mimetic peptide.