VITEK, MICHAEL P.,MCKENNA, SUZANNE E.,SELF, CHRISTOPHER R.
申请号：
CA2578146
公开号：
CA2578146C
申请日:
2005.09.02
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Novel ApoE peptide derivatives and ApoE-protein transduction domain conjugatesare disclosed which are useful for treating disorders including CNSinflammation, traumatic brain injury, inflammatory bowel disease (also knownas Crohn's Disease or ulcerative colitis), cerebral ischemia, atherosclerosis,sepsis, multiple sclerosis and arthritic diseases, Alzheimer's Disease andother brain disorders. The invention encompasses methods for protectingsubjects having undergone irradiation or radiotherapy by administration ofApoE or at least one ApoE mimetic peptide.
