Disclosed are: a composition comprising royal jelly and pomegranate pericarp or an extract thereof, said composition being a cosmetic, a food, a beverage, a drug or a quasi-drug； a composition comprising propolis and pomegranate or an extract thereof, said composition being a cosmetic, a food, a beverage, a drug or a quasi-drug； an mTOR inhibitor comprising royal jelly and/or propolis and pomegranate or an extract thereof； and a composition against aging, against fatigue, against stress, for improving metabolism, for dieting, for humidifying, for improving skin firmness or glossiness, for preventing cognitive impairment, for immunosuppression, against allergy, for preventing cancer or for inhibiting cancer progress, said composition comprising royal jelly and/or propolis and pomegranate or an extract thereof.本發明係關於一種組成物，其係化妝品、飲食品、醫藥品、或醫藥部外品(Quasi-drug)，其特徵係含有蜂王漿、及石榴皮或其萃取物；一種組成物，其係化妝品、飲食品、醫藥品、或醫藥部外品，其特徵係含有蜂膠、及石榴或其萃取物；一種mTOR抑制劑，其特徵係含有蜂王漿及/或蜂膠、以及石榴或其萃取物；以及一種組成物，其特徵係含有蜂王漿及/或蜂膠、以及石榴或其萃取物，作為抗老化用、抗疲勞用、抗壓用、代謝改善用、減重用、保濕用、皮膚彈性或光澤改善用、認知功能減退預防用、免疫抑制用、抗過敏用、預防癌症用、或抑制癌症擴散用之組成物。
