Neuromodulation systems in accordance with embodiments of the invention can use a feed-forward common-mode cancellation (CMC) path to attenuate common-mode (CM) artifacts appearing at a voltage input, thus allowing for the simultaneous recording of neural data and stimulation of neurons. In several embodiments of the invention, the feed-forward CMC path is utilized to attenuate the common-mode swings at Vin,CM, which can restore the linear operation of the front-end for differential signals. In several embodiments, the neuromodulation system may utilize an anti-alias filter (AAF) that includes a duty-cycles resistor (DCR) switching at a first frequency f1, followed by a DCR switching at a second frequency f2. The AAF allows for a significantly reduced second frequency f2 that enables the multi-rate DCR to increase the maximum realizable resistance, which is dependent upon the frequency ratio f1/f2.
