This invention discloses an application of solanum muricatum leaf extract used for treating and/or preventing high blood pressure and a composition for preventing high blood pressure related diseases. By dosing an effective amount of the solanum muricatum leaf extract disclosed by this invention to an individual, the blood pressure of the individual can be maintained stable or the blood pressure rise of the individual can be suppressed, so as to achieve efficacies of preventing and/or treating high blood pressure and preventing high blood pressure related diseases.本發明係揭露一種以香瓜茄葉萃取物用於製造治療或/及預防高血壓、預防與高血壓相關疾病之組合物之用途。藉由投予一有效量之本發明所揭香瓜茄葉萃取物至一個體時，係能夠使該個體之血壓維持穩定，或是抑制該個體血壓上升，以達到預防或/及治療高血壓、預防與高血壓相關疾病之功效。
