COMPOUND, USE OF THE SAME, METHOD TO TREAT BACTERIAL INFECTION IN A HOT BLOOD ANIMAL, PHARMACEUTICAL COMPOSITION, AND PROCESS FOR PREPARING A COMPOUND.

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专利权人:

ASTRAZENECA AB.

发明人:

GREGORY STEVEN BASARAD,JAQUES DUMAS,PAMELA HILL

申请号：

BRPI0813427

公开号：

BRPI0813427A2

申请日:

2008.07.01

申请国别(地区):

BR

年份:

2014

代理人:

摘要：

In one aspect, the present invention relates to compounds of Formula (I) and to pharmaceutically acceptable salts thereof, wherein: n is 1 to 4； and R3 in each occurrence is independently selected from &mdash；X&mdash；R5, &mdash；W&mdash；R6, &mdash；C(O)&mdash；N(R3a)&mdash；S(O)2&mdash；R3b, &mdash；C(R3a)&boxH；N&mdash；R3y, C(R3a)&boxH；N&mdash；N(R3a)&mdash；C(O)&mdash；R3b, C(R3a)&boxH；N&mdash；N(R3a)&mdash；C(O)2&mdash；R3b, &mdash；C(R3a)&boxH；N&mdash；N(R3y)2, &mdash；C(R3a)&boxH；N&mdash；N(R3a)&mdash；C(O)&mdash；N(R3y)2, &mdash；C(NR3a)2)&boxH；N&mdash；R3y, &mdash；C(N(R3a)2)&boxH；N&mdash；OR3y, &mdash；C(N(R3a)2)&boxH；N&mdash；C(O)&mdash；R3b, &mdash；C(N(R3a)2&boxH；N&mdash；S(0)2&mdash；R3b, &mdash；C(N(R3a)2)&boxH；N&mdash；CN, &mdash；N&boxH；C(R3y)2, &mdash；N(R3a)&mdash；S(O)2&mdash；N(R3y)2, &mdash；N(R3a)&mdash；N(R3y2, &mdash；N(R3a)&mdash；C(O)&mdash；N(R3y)2, &mdash；N(R3a)&mdash；C(O)&mdash；N(R3a)&mdash；S(O)2&mdash；R3b, &mdash；N(R3a)&mdash；C(R3a)&boxH；N(R3y), &mdash；N(R3a)&mdash；C(R3a)&boxH；N&mdash；OR3y, &mdash；N(R3a)&mdash；C(R3a)&boxH；N&mdash；C(O)&mdash；R3b, &mdash；N(R3a)&mdash；C(R3a)&boxH；N&mdash；S(O)2R&mdash；3b, &mdash；N(R3a)&mdash；C(R3a)&boxH；N&mdash；CN, &mdash；N(R3a)&mdash；C(N(R3a)2)&boxH；N&mdash；R3y, &mdash；N(R3a)&mdash；C(N(R3a)2)&boxH；N&mdash；OR3y, &mdash；N(R3a)&mdash；C(N(R3a)2)&boxH；N&mdash；C(O)&mdash；R3b, &mdash；N(R3a)&mdash；C(N(R3a)2)&mdash；N&mdash；S(O)2&mdash；R3b, &mdash；N(R3a)&mdash；C(N(R3a)2)&mdash；N&mdash；CN, &mdash；O&mdash；C(O)&mdash；R3, and &mdash；Si(R3b)3； to methods of using them to treat bacterial infections, and to methods for their preparation.

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