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HLA-A*1101限制的WT1肽及含有其的藥物組合物
专利权人:
INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY INC.
发明人:
SUGIYAMA, Haruo
申请号:
HK16109237.6
公开号:
HK1221252A
申请日:
2016.08.03
申请国别(地区):
HK
年份:
2017
代理人:
摘要:
The present invention relates to an HLA-A*1101-restricted WT1 peptide, specifically, a peptide comprising an amino acid sequence consisting of 9 contiguous amino acids from a WT1 protein, wherein the peptide has an ability to bind to an HLA-A*1101 molecule, and has an ability to induce a CTL. The present invention also relates to a peptide dimer having an ability to bind to an HLA-A*1101 molecule and having an ability to induce a CTL, in which two peptide monomers each comprising an amino acid sequence consisting of 9 contiguous amino acids from a WT1 protein and comprising at least one cysteine residue are bound to each other through a disulfide bond. Furthermore, the present invention relates to a polynucleotide encoding the peptide, a pharmaceutical composition for the treatment and/or prevention of a cancer comprising the same and the like.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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