The present invention discloses a nourishing and relaxing wrinkle-resisting hand cream and a manufacturing method thereof. The manufacturing method includes the steps of: (1) adding ginseng water solution, sodium hyaluronate, EDTA-2Na and allantoin into a stirring pan, and heating and slowly stirring the same and, when the temperature is raised to 80 DEG C, stopping heating while continuing stirring until becoming completely dissolved and transparent (2) continuing stirring and, when the temperature is lowered to 40 DEG C, adding NaOH (3) continuing stirring and adding ceramide, D-panthenol, water jojoba oil, hexapeptide, VE, lubrajel, amino acid pentapeptide, EGF, lipoic acid lipid nanoparticles, nano-vitamin A, coenzyme Q10, buckeye extract liquid, biological polysaccharide-4, pentadiol, lubrajel, and centella asiatica extract liquid and (4) after the temperature is lowered to 30 DEG C, adding anti-sensitizer for output. The clinical experiment proves that the present invention is provided with a unique effect of obviously nourishing, relaxing and repairing the hand skin wrinkles after a long term usage without encountering any side effect.本發明公開了一種滋養舒緩防皺護手霜及其製備方法,其包括以下步驟,將人參水溶液、透明質酸鈉、EDTA-2Na、尿囊素加入到攪拌鍋中,加熱,緩慢攪拌,直至溫度升到80℃停止加熱,繼續攪拌,直到完全溶解透明;(2)繼續攪拌,待溫度降到40℃加入NaOH;(3)繼續攪拌,加入神經醯胺、D-泛醇、水溶性荷荷巴油、六胜肽、VE、蘆芭膠、胺基酸五肽、EGF、硫辛酸脂質奈米粒、奈米維生素A、輔酶Q10、七葉樹萃取液、生物多糖膠-4、戊二醇、蘆芭膠、積雪草萃取液;(4)待溫度降到30°後,加入抗敏劑,出料。臨床實驗證明,本發明長期使用後具有明顯的滋養舒緩修復手部肌膚皺紋的獨特效果,且無任何副作用。無
