The invention relates to the technical field of detection, and provides a method and system for measuring oxyhemoglobin saturation in blood. The method includes the steps that two parallel light emitting diodes are controlled to periodically emit red light and infrared light to a finger to be detected the red light and the infrared light which are projected through the finger are detected and converted into a red light electrical signal and an infrared light electrical signal pulse components in the two electrical signals are separated out to obtain separated red light variable quantity in one period and infrared light variable quantity in one period the oxyhemoglobin saturation in blood is calculated according to the red light variable quantity and the infrared light variable quantity the oxyhemoglobin saturation is amplified, filtered, and then converted into a digital signal by an analog-digital converter for display. According to the technical scheme, the method and system have the advantages of non-invasive detection and real-time detection.本發明適用於檢測技術領域,提供了一種血液中血氧飽和度的測量方法及系統,該方法包括:控制兩個並列的發光二極體向待測手指週期性的發出紅光和紅外光;檢測投射過該手指後的紅光和紅外光,並將該投射過該手指後的紅光和紅外光轉換成紅光電信號和紅外光電信號;將兩個電信號中的脈動成分分離出來得到分離後的一個週期的紅光變化量和一個週期的紅外光變化量;依據該紅光變化量和紅外光變化量計算出血液中血氧飽和度;將該血氧飽和度經過放大和濾波後,由模數轉換器轉換成數位信號顯示。本發明提供的技術方案具有無創檢測,即時檢測的優點。