PROBLEM TO BE SOLVED: To provide natural extract based drugs, particularly antioxidants that correspond to wide range of various skin disorders, such as wrinkles, dullness, loss of smooth skin texture, decreased elasticity, stains, and freckles, and can prevent, treat, or improve them.SOLUTION: The invention provides an antioxidant extracted from Connaraceae, Connarus ruber with a polar solvent. As an extraction site, particularly, a bark is preferable and the extraction solvent preferably contains polyhydric alcohol.SELECTED DRAWING: None