CO-CRISTAL DE PIPÉRACILLINE SODIUM ET DE SULBACTAM SODIUM ET SON PROCÉDÉ DE PRÉPARATION, ET COMPOSITIONS PHARMACEUTIQUES LE CONTENANT ET LEURS UTILISATIONS
Beijing Xintianyu Technology Development Co.; Ltd.
发明人:
申请号:
EP12884606.0
公开号:
EP2896625A1
申请日:
2012.09.14
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
Provided in the present invention are a cocrystal of piperacillin sodium and sulbactam sodium and preparation method thereof, as well as pharmaceutical compositions containing the same and uses thereof in treating infections caused by drug-resistant bacteria, such as a "super bacterium" producing NDM-1 and the like. The cocrystal of piperacillin sodium and sulbactam sodium contains diffraction angles of 14.24°, 16.58°, 16.79°, 17.77°, 19.20°, 20.21°, 20.39°, 23.06°, 27.86° and 32.16° represented by 2θ in an X-ray powder diffraction analysis spectrum.