BABCOCK DAVID E,LUNDQUIST SEAN,OPPERMAN GARY,TORGUSON ADRIYN,JENTZ TIM
申请号：
IN201747003959
公开号：
IN201747003959A
申请日:
2017.02.03
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
Embodiments of the disclosure include coatings comprising an oligomerized polyphenol layer. The oligomerized polyphenol layer can be used as an intermediate coated layer on a medical device that hydrogen bonds to a synthetic or natural polymer which in turn can be used as a top coat or further associated with another coated layer. The multilayered coatings can provide properties such as hemocompatibility or lubricity. In other embodiments the oligomerized polyphenol layer is used on a medical device as a hemostatic layer configured to contact blood and promote coagulation. The oligomerized polyphenol layer can also be used on the inner surface (e.g. inner diameter) of a medical device to prevent bacterial adherence. The oligomerized polyphenol layer can also be used on the surface of a in vitro diagnostic article or a cell culture device to promote adsorption of a biological molecule.
