Matrix metalloprotease inhibitors based on arylsulfonamides

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专利权人:

ノバルティス アーゲー

发明人:

クラウス・エーアハルト,レスリー・ワイトン・マクワイア,パスカル・リゴリエ,オリヴィエ・ロジェル,マイケル・シュルツ,ルーベン・アルバート・トマシ

申请号：

JP2011501191

公开号：

JP5490092B2

申请日:

2009.03.23

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

The present invention provides a compound of formula (I): said compound is inhibitor of MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12 and/or MMP-13, and thus can be employed for the treatment of a disorder or disease characterized by abnormal activity of MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12 and/or MMP-13. Accordingly, the compound of formula (I) can be used in treatment of disorders or diseases mediated by MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12, and/or MMP-13. Finally, the present invention also provides a pharmaceutical composition.

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