OLBRICH, CARSTEN,PLITZKO, MATTHIAS,LUY, BERNHARD,SCHNEID, STEFAN CHRISTIAN
申请号：
CA3004789
公开号：
CA3004789A1
申请日:
2016.11.04
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
A method for the production of freeze-dried pellets comprising factor VIII comprises the steps of: a) freezing droplets of a solution comprising factor VIII to form pellets； b) freeze-drying the pellets； wherein in step a) the droplets are formed by means of droplet formation of the solution comprising factor VIII into a cooling tower which has a temperature-controllable inner wall surface and an interior temperature below the freezing temperature of the solution and wherein in step b) the pellets are freeze-dried in a rotating receptacle which is housed inside a vacuum chamber.
