OLBRICH, Carsten,PLITZKO, Matthias,LUY, Bernhard,SCHNEID, Stefan Christian
申请号：
SG11201803637P
公开号：
SG11201803637PA
申请日:
2016.11.04
申请国别(地区):
SG
年份:
2018
代理人:
摘要：
A method for the production of freeze-dried pellets comprising factor VIII comprises the steps of: a) freezing droplets of a solution comprising factor VIII to form pellets； b) freeze-drying the pellets； wherein in step a) the droplets are formed by means of droplet formation of the solution comprising factor VIII into a cooling tower which has a temperature-controllable inner wall surface and an interior temperature below the freezing temperature of the solution and wherein in step b) the pellets are freeze-dried in a rotating receptacle which is housed inside a vacuum chamber.
