Joseph W. Franses;Helen Marie Nugent;Elazer R. Edelman;Angelo Manuel De Almeida Cardoso
发明人:
Joseph W. Franses,Elazer R. Edelman,Angelo Manuel De Almeida Cardoso,Helen Marie Nugent
申请号:
US13147695
公开号:
US20120027858A1
申请日:
2010.02.04
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention relates to composition and a method of using the composition for modulating proliferation, invasiveness, the expression of a biomarker of an abnormal cell, of reducing the risk of a patient cell becoming abnormal, or of modulating proliferation of a carcinoma-associated fibroblast or of a tumor-associated macrophage. The invention also relates to a method of culturing the composition to produce molecules that modulate abnormal cell proliferation, invasiveness, or metastasis. The composition comprises a biocompatible matrix and cells engrafted thereon.