The present invention relates to novel strains of Streptomyces microflavus and methods of their use for controlling diseases or pests of a plant. The invention also relates to a fermentation broth obtained by cultivating a gougerotin producing Streptomyces strain, wherein the fermentation broth contains at least about 2 g/L gougerotin. The invention also relates to a method of producing a fermentation broth of a gougerotin producing Streptomyces strain, wherein the fermentation broth contains at least about 2 g/L gougerotin, the method comprising cultivating the Streptomyces strain in a culture medium containing a digestible carbon source and a digestible nitrogen source under aerobic conditions.本發明係關於細黃鏈黴菌之新穎菌株及其用於控制植物之疾症或有害生物之方法。本發明亦係關於藉由培養產生谷氏菌素之鏈黴菌菌株獲得之發酵液,其中該發酵液含有至少約2g/L谷氏菌素。本發明亦係關於產生產生谷氏菌素之鏈黴菌菌株之發酵液之方法,其中該發酵液含有至少約2g/L谷氏菌素,該方法包含在有氧條件下在含有可消化碳源及可消化氮源之培養基中培養該鏈黴菌菌株。