Mart Saarma,Mati Karelson,Maxim Bespalov,Mehis Pilv
申请号:
US13514906
公开号:
US08901129B2
申请日:
2010.12.13
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Disclosed are compounds and methods for treating neurological and other disorders by administering to a subject in need thereof an effective amount of a compound having binding and/or modulation specificity for GFRα receptor molecules, which can be mimetics of glial-derived neurotrophic factor (GDNF) family ligands (GFLs), GFRα/RET signaling pathway agonists, and/or direct RET agonists (activators).