Anders Nykjær;Simon Glerup;Peder Søndergaard Madsen;Ditte Olsen;Claus Munck Petersen
发明人:
Anders Nykjær,Simon Glerup,Peder Søndergaard Madsen,Claus Munck Petersen,Ditte Olsen
申请号：
US13702692
公开号：
US20130115212A1
申请日:
2011.06.14
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to a method to increase the survival of neurons by modulating the interaction between SorLA and GDNF-family ligand receptors. The agent used to modulate the interaction between the SorLA and GDNF-family ligand receptors are selected from proteins, peptides, antibodies or small organic compounds. The invention also relates to a pharmaceutical compositions comprising these agent as well as the use of said agent or pharmaceutical composition in the treatment of a disease associated with the loss of neurons and/or wherein the survival of neurons are desired.
