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TROPOLONE COMPOUNDS FOR TREATING OR PREVENTING RETROVIRAL INFECTION
专利权人:
John A. Beutler
发明人:
John A. Beutler,Stuart F.J. LeGrice,Craig Thomas,Jian-Kang Jiang,Suhman Chung,Jennifer Wilson
申请号:
US14116423
公开号:
US20140249181A1
申请日:
2012.05.10
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Disclosed are compounds that inhibit RNase H activity of retroviruses, for example, a compound of formula (I) wherein R1, R2, and R3 are as described herein, as well as pharmaceutically acceptable salts, solvates, stereoisomers, and prodrugs thereof. Pharmaceutical compositions comprising such compounds, as well as methods of use, and treatment or prevention of infection by human immunodeficiency virus (HIV).
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