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Compounds for the treatment and prevention of infections
专利权人:
Brown University
发明人:
Walter Atwood,Christian Nelson,Jason K. Sello,Daniel William Carney
申请号:
US14415177
公开号:
US09695156B2
申请日:
2013.07.15
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Provided herein are compounds of Formula (I) or (II): (I) (II) pharmaceutically acceptable salts, tautomers, prodrugs, and stereoisomers thereof, and pharmaceutical compositions thereof, wherein X, RN, R1, R3, R4, p, and m are as defined herein. Such compounds and compositions have been found useful in the treatment or prevention of viral infections, e.g., polyomaviral infections, and are further envisioned useful in treatment or prevention of other pathogenic conditions associated with endosomal trafficking. Methods of treating or preventing an infection by a pathogen secreting an AB5 toxin is also contemplated.
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