An embodiment of the present invention provides a mask, ventilation therapy equipment and a method executed based on the ventilation therapy equipment, and belongs to the field of ventilation therapy equipment. The mask comprises a mask body, acquisition units and output units, wherein the acquisition units are arranged on the mask body and are used for acquiring eye movement data of the eyes of a user; the eye movement data comprises action data of the eyes of the user; and the output units are connected with the acquisition units, and are used for outputting the eye movement data. By the mask, a ventilation therapy equipment system and the method executed based on the ventilation therapy equipment system, the operation intention expressed by the user with the eyes can be recognized so as to carry out follow-up control on the ventilation therapy equipment, and the user experience is greatly enhanced.